WHAT WE DO
The influx of Ca2+ through Ca2+ selective channels drives the contraction of cardiac and skeletal muscle, and release of hormones and neurotransmitter. We study how these Ca2+ channels function, how they are regulated by different signalling events, and how disease mutations lead to channel malfunction. We employ a combination of structural biology, electrophysiology, and various biophysical methods.
LATEST NEWS: THE STRUCTURE OF THE RYANODINE RECEPTOR N-TERMINAL DISEASE HOT SPOT
Check out the video: CPVT mutations